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Early enteral nutrition in septic shock is theoretically beneficial, but trials have yielded conflicting results. Defining the optimal timing and patient selection for enteral nutrition remains a critical challenge.

Septic shock management may be entering a new era of personalized care, moving beyond rigid feeding protocols. New evidence suggests that delaying enteral nutrition in some septic shock patients may improve outcomes.

Initiating enteral nutrition in septic shock patients is a tightrope walk; too early, and you risk gut ischemia, too late, and you starve the patient. The key is vigilant bedside assessment of gut perfusion to guide individualized feeding strategies.