Innovation

Ventilation: Why static guidelines fail dynamic patients

Continuous-improvement ventilation relies on real-world data to refine protocols and enhance patient outcomes, moving beyond static guidelines.

OSA: Why AHI alone isn't predicting your patients' heart risk

The apnea-hypopnea index (AHI) remains the standard for obstructive sleep apnea diagnosis, but its limitations in predicting cardiovascular outcomes are clear.

Alpha-1 Antitrypsin Deficiency: Beyond augmentation, a new path

Advancements in Alpha-1 Antitrypsin Deficiency (AATD) therapies focus on restoring functional AAT levels and achieving clinically meaningful endpoints beyond simple protein augmentation.

Stop missing ILD: AI reveals what the eye can't see

Integrating artificial intelligence with clinical expertise can accelerate the identification of interstitial lung disease, potentially improving patient outcomes.

Bronchoscopy training: Why 'hundreds of procedures' may no longer be enough

AI integration into flexible bronchoscopy training aims to improve procedural proficiency and diagnostic accuracy for respiratory specialists.

Could immune system modulation be the next frontier in skincare?

Emerging research suggests that targeting immune pathways could offer novel strategies for managing chronic skin conditions, moving beyond symptomatic relief.

Givinostat: Targeting the Downstream Disease in Duchenne Muscular Dystrophy

Givinostat, a histone deacetylase inhibitor, offers a non-genetic approach to Duchenne muscular dystrophy by addressing downstream disease mechanisms.

RET-altered thyroid cancer: how selective inhibitors changed advanced disease

The advent of selective RET inhibitors has significantly improved outcomes for patients with advanced RET-altered thyroid cancer. These targeted therapies address a critical unmet need in a previously challenging disease landscape.

Gepotidacin: A New Oral Option for Uncomplicated UTIs in Adolescents

Gepotidacin, a first-in-class oral antibiotic, received approval in 2025 for uncomplicated UTIs in female patients aged 12 years and older and weighing at least 40 kg.