Insights

Respiratory care: Why neurology's long-acting therapies could be key

Insights from multiple sclerosis treatment paradigms offer a framework for developing ultra-long-acting therapies in respiratory care, addressing adherence and disease progression.

Rethink PDE inhibition in COPD: Not all isoforms are equal

Phosphodiesterase (PDE) inhibitors offer therapeutic potential in COPD, but adverse effects, particularly nausea with PDE4 inhibitors and cardiovascular risks with chronic PDE3 inhibition, limit their broader application.

RSV and COVID-19 vaccines: Why are we still underestimating their impact?

Vaccination against RSV and COVID-19 offers a critical strategy for mitigating the burden of respiratory diseases, particularly in vulnerable populations.

Severe asthma: Why targeted therapies miss some Type 2 patients

Emerging clinical insights suggest the distal airways play a more central role in Type 2 severe asthma pathophysiology than previously understood.

COPD exercise limits: Is your oxygen therapy doing enough?

High-flow humidified oxygen improved exercise endurance and reduced dyspnea in patients with advanced COPD compared to conventional low-flow oxygen.

Chronic lung disease: Why early diagnosis still isn't enough

Managing chronic lung diseases presents complex challenges, from accurate diagnosis to optimising long-term treatment strategies and addressing patient adherence.

COPD: Why focusing only on exacerbations misses the bigger picture?

COPD management extends beyond preventing exacerbations, encompassing symptom burden, exercise capacity, and quality of life for a holistic patient approach.

Epithelial health: more than a symptom of chronic inflammation?

Maintaining epithelial barrier integrity is emerging as a critical factor in achieving disease remission, moving beyond traditional symptom management in chronic inflammatory conditions.

Chronic respiratory disease: Why diagnosis often comes too late

Understanding the patient journey for chronic respiratory diseases in resource-limited settings reveals significant diagnostic and treatment delays, impacting long-term outcomes.