Oncology

The real reason joint oncology practices need explicit protocols

Running a joint oncology clinic presents unique challenges and benefits, requiring careful navigation of professional boundaries and patient dynamics.

ARHGAP36: A new survival predictor for neuroblastoma patients

High ARHGAP36 levels predict improved 5-year survival in neuroblastoma patients, linking FOXC1-induced expression to altered Hedgehog signaling.

Jideytro offers new hope for ROS1-positive NSCLC after prior therapy

The FDA approved Jideytro for previously treated ROS1-positive non-small cell lung cancer, providing a new option for this rare subtype.

Molecular Profiling Refines Salivary Gland Tumor Diagnosis

Molecular profiling improves the diagnostic accuracy and identification of actionable alterations in complex salivary gland tumors, complementing traditional histopathology.

How non-animal models are redefining oncology drug safety

The FDA issued draft guidance to reduce animal testing for oncology drugs, allowing sponsors to use non-animal methods for certain safety and efficacy assessments.

Forget sterile tumors: Cancers house unique microbiomes

A comprehensive analysis of over 17,000 tumor samples confirms distinct microbial signatures across 35 cancer types, influencing prognosis and treatment response.

Sitting for Long Stretches Linked to Higher Cancer Mortality Risk

Extended sedentary time increases the risk of death from cancer, particularly for specific cancer types, independent of physical activity levels.

Cancer survival improves. Why are rural outcomes still worsening?

Patients in rural areas face significant disparities in cancer treatment access and prevention, leading to worse outcomes compared to their urban counterparts.

South African Scientists Decipher Cancer's Survival Strategy

Researchers in South Africa have uncovered a key mechanism cancer cells exploit to evade immune detection, offering new targets for therapeutic intervention.