Gastroenterology

Beyond statins: The counterintuitive path to cutting pancreatitis risk

ApoC-III inhibition with plozasiran reduced triglycerides by 53%-58% and showed a borderline 17% reduction in pancreatitis events in severe hypertriglyceridemia.

Why coeliac disease drug development keeps hitting a wall

Developing new treatments for coeliac disease has proven exceptionally difficult, despite a clear unmet need and growing understanding of its immune mechanisms.

Persistent Celiac Symptoms: What to Suspect Beyond Gluten Exposure

Persistent symptoms on a gluten-free diet in celiac disease patients necessitate a work-up for refractory celiac disease, with specific serum markers identifying those needing endoscopy.

IBD overlap changes colorectal cancer screening for rare subtypes

Inflammatory bowel disease significantly worsens recurrence-free survival in rare colorectal carcinoma subtypes, particularly enteroblastic CRC, necessitating revised screening protocols.

Why traditional sleep aids miss the gut-sleep link after hydrogen supplementation?

Emerging research explores the intricate link between gut microbiota composition and sleep quality, particularly after hydrogen supplementation.

Dupilumab improves inflammation in eosinophilic gastritis, but what about symptoms?

Dupilumab significantly reduced eosinophil counts in patients with eosinophilic gastritis, addressing a key inflammatory driver of the disease.

Cannabinoid hyperemesis: Why cannabis users self-medicate with hot showers

Cannabinoid hyperemesis syndrome presents as cyclic vomiting in chronic cannabis users, a diagnosis often delayed due to its mimicry of other conditions.

Shorter octreotide could ease variceal bleed burden for your patients

The optimal duration of octreotide infusion for acute esophageal variceal bleeding has been a subject of debate, with current guidelines recommending a 2-5 day course.

Your chronic GI patients: Don't overlook this key dietary history detail

A physician's prolonged suffering from severe gastrointestinal distress stemmed from a surprising, self-imposed dietary choice, highlighting the complexities of patient adherence.