Practice

Lymphatic malformations: Is your management approach outdated?

Lymphatic malformations, particularly cystic hygromas, demand a nuanced management approach, balancing observation with targeted interventions.

Ceftriaxone: Navigating Dosing, Indications, and Adverse Effects in Practice

Ceftriaxone, a third-generation cephalosporin, requires careful consideration of dosing, indications, and potential adverse effects for optimal patient outcomes.

Heart Failure Treatment in 2026: A Clinical Overview

Heart failure management has changed substantially over the past decade. This clinical overview covers the four pillars of guideline-directed medical therapy, the role of device therapy, and emerging treatments entering practice in 2026.

What Is CAR-T Cell Therapy? Mechanism, Approved Indications, and Key Evidence

CAR-T cell therapy reprogrammes a patient's own T cells to seek and destroy cancer cells. Here is what clinicians need to know about how it works, which cancers it is approved for, and what the evidence shows.

What Is an SGLT2 Inhibitor? Mechanism, Indications, and Evidence

SGLT2 inhibitors block renal glucose reabsorption to lower blood sugar and protect the heart and kidneys. A clinical primer on mechanism, approved agents, key trial evidence, and safety.

Think cardiotoxicity is old news? Modern cancer therapy says otherwise

Cardiotoxicity from cancer treatments demands vigilant monitoring and proactive management, especially with immune checkpoint inhibitors and 5-FU.

Non-drug strategies for post-op delirium after cardiac surgery

Multicomponent non-pharmacological interventions reduce post-operative delirium incidence and severity in cardiac surgery patients.

C3G: Pegcetacoplan or iptacopan? Why indirect data complicates your choice

Indirect comparisons suggest pegcetacoplan may offer superior efficacy in C3 glomerulopathy, but head-to-head trials are absent.

Keeping Medicines Safe in Heat: Essential Advice for GPs

High temperatures compromise drug stability and efficacy. GPs must advise patients on proper medicine storage to prevent treatment failures and adverse events.