Guidelines

ICD-11: What European GPs need to know about the new classification system

The ICD-11 system introduces significant changes to disease classification, impacting coding for conditions like hidradenitis suppurativa and neonatal encephalopathy.

Duke-ISCVID 2023: What changed for endocarditis diagnosis at the bedside?

The 2023 Duke-ISCVID criteria update refined diagnostic pathways for infective endocarditis, integrating advanced imaging and microbiological techniques to improve accuracy.

Navigating dental trauma in children: How guidelines handle the immature apex

Managing dental trauma in children with immature apices presents unique challenges, requiring careful consideration of pulp vitality and root development.

Lupus Nephritis: How Low Can Steroid Doses Go?

Lower-dose steroid regimens in lupus nephritis are increasingly favored, balancing efficacy against the substantial burden of glucocorticoid toxicity.

Lower-dose steroids in lupus nephritis: How far has guidance truly moved?

Guideline recommendations for lupus nephritis have shifted towards lower-dose steroid regimens, aiming to balance efficacy with reduced toxicity.

Antihistamine-refractory urticaria: when standard care falls short

Current guidelines for chronic urticaria recommend step-up therapy for patients who do not respond to standard antihistamine doses, escalating to higher doses or adding biologics.

Immunotherapy Reshapes First-Line Treatment for Advanced Endometrial Cancer

Adding pembrolizumab to chemotherapy significantly improved progression-free survival in advanced or recurrent endometrial cancer, regardless of mismatch repair status. These findings support updated first-line treatment guidelines.

Cognitive Care in Sickle Cell Disease: New Standards Target Overlooked Burden

New standards aim to integrate cognitive care into sickle cell disease management, addressing a significant, often overlooked, burden on patients.

Bundibugyo virus: Why community trust is the only vaccine we have

Effective community engagement is critical for containing Bundibugyo virus outbreaks, according to new WHO operational guidance.