Research

Pediatric dentists are increasingly exploring phytotherapy, but the strength of evidence supporting its use remains unclear. This review highlights the need for more rigorous, randomized controlled trials to validate the efficacy and safety of herbal interv...

Current understanding of severe to profound sudden sensorineural hearing loss prognosis is often hampered by heterogeneous retrospective data. Clinicians must exercise caution when applying pooled meta-analysis results to individual patient counseling witho...

In preventive health services, a quasi-experimental analysis from India examines how health insurance shifts cardiometabolic risk through financial access to screening and treatment . Effect estimates appear modest and heterogeneous, with several 95% CIs ov...

In severe aortic regurgitation, investigators assessed whether the Genereux cardiac damage staging classification predicts left ventricular reverse remodeling after surgical or transcatheter intervention. Using predefined echocardiographic endpoints and mul...

Heart transplant recipients face progressive renal impairment under calcineurin inhibitor exposure. The randomized DAPARHT trial evaluates dapagliflozin to preserve kidney function, with prespecified endpoints including eGFR slope, albuminuria, and acute ki...

Cardiology prescribing was examined by linking CMS Open Payments with NCDR PINNACLE to evaluate whether industry transfers to physicians correlate with use of PCSK9 inhibitors, ARNi, and DOACs. Receipt and magnitude of payments were associated with greater ...

AIVUS-CAA targets automated intravascular ultrasound processing for coronary artery anomalies , combining segmentation and quantification to derive lumen, vessel, and plaque metrics. Benchmarked against expert annotations and reference measurements, the sof...

In obesity and related metabolic disease, stress hormones drive lipogenesis and low-grade inflammation. Tea seed saponin tempered cortisol -triggered lipid accumulation and inflammatory signaling in human cells, reducing lipogenic and cytokine readouts unde...

In myocardial infarction , pentameric C-reactive protein may amplify ischemia-reperfusion injury via complement activation and opsonization of damaged myocardium. The CRP-STEMI randomized trial tests selective apheresis to lower circulating CRP as an adjunc...

Amyotrophic lateral sclerosis imposes profound fatigue and mobility limits that shape willingness to join clinical research . Interviews illuminated how energy conservation, travel burden, invasive procedures, and altruism interact. Key finding: participant...