The Life Science Feed
Deep dives with clinicians, researchers, and industry leaders.
All episodes
Forget sterile tumors: Cancers house unique microbiomes
A comprehensive analysis of over 17,000 tumor samples confirms distinct microbial signatures across 35 cancer types, influencing prognosis and treatment response.
ARHGAP36: A new survival predictor for neuroblastoma patients
High ARHGAP36 levels predict improved 5-year survival in neuroblastoma patients, linking FOXC1-induced expression to altered Hedgehog signaling.
Sitting for Long Stretches Linked to Higher Cancer Mortality Risk
Extended sedentary time increases the risk of death from cancer, particularly for specific cancer types, independent of physical activity levels.
The real reason joint oncology practices need explicit protocols
How non-animal models are redefining oncology drug safety
Jideytro offers new hope for ROS1-positive NSCLC after prior therapy
Nearly 1 in 10 With Primary Biliary Cholangitis Have CKD
Chronic kidney disease affects 9.5% of patients with primary biliary cholangitis, with hypertension and older age driving incidence.
Metabolic Dysfunction Associated Steatotic Liver Disease: An Overview
A recent review outlines the mechanisms, diagnosis, and management of metabolic dysfunction associated steatotic liver disease (MASLD) in adults.
Smartphones and Pacemakers: Separating Fact from Electromagnetic Fiction
Modern smartphones pose minimal risk of electromagnetic interference with pacemakers and ICDs, provided a safe distance is maintained.
For atrial fibrillation, integrated pathways may beat individual fixes
The AF-CARE pathway, a comprehensive, integrated management strategy, aims to improve outcomes for atrial fibrillation patients by standardising care.
Pulsed Field Ablation: A New Frontier for Atrial Fibrillation?
Pulsed field ablation offers a novel, non-thermal approach to cardiac tissue destruction, leveraging irreversible electroporation for targeted cell death in arrhythmias.
A Simpler Score for Coronary Calcium: Does it Help Predict Risk?
Severe VT in ischaemic cardiomyopathy: Why current care isn't enough
How lipid packing dictates caveolae stability at the plasma membrane
Your obesity patients deserve more than just weight loss goals
Modern obesity treatment is shifting focus from simple weight loss to more meaningful clinical endpoints, reflecting a broader understanding of the disease's impact.
CGM offers tighter glucose control for type 2 diabetes on dialysis
Continuous glucose monitoring (CGM) improves glycemic control in patients with type 2 diabetes undergoing hemodialysis, a population often overlooked in diabetes management.
Katie Couric's Transient Global Amnesia: A 'Big, Black Hole' Event
Katie Couric recently described an episode of transient global amnesia, a sudden, temporary loss of memory that can be alarming but is typically benign.
Repeated head impacts: What they mean for dementia risk
Repeated blows to the head in contact sports significantly increase the risk of dementia, particularly in former professional athletes.
Molecular Profiling Refines Salivary Gland Tumor Diagnosis
Cardiovascular risk: Why men die earlier, women live sicker
Chronic Hepatitis Delta Virus: Why direct viral targeting matters now
Alcohol and Sugar: A Dual Metabolic Challenge for Patients
Liver Transplant Studies Retracted Over Organ Harvesting Concerns
Liver-Directed Treatment Shows Efficacy in Metabolic Dysfunction
EHR-derived marker flags liver transplant recipients at high risk of early death
EHR data identifies liver transplant patients at high risk of early graft loss
Weight-Loss Jabs May Create a New Kind of Yo-Yo Dieting
GLP-1s and lifestyle: a new path to stronger bones?
What Is an SGLT2 Inhibitor? Mechanism, Indications, and Evidence
Weekly growth hormone therapy: a safer path to long-term height gains?
Metabolic Syndrome: Is it accelerating your patients' brain aging?
Tzield expands its reach: A new option for recently diagnosed pediatric type 1 diabetes
AXS-05 Reduces Agitation in Alzheimer's Disease Patients
Beyond screen time: How short videos rewire dopamine pathways
Roche Halts Huntington's Gene-Silencing Programs
Football Headers Linked to Cognitive Decline, Neurodegeneration
Chronic Migraine: Is the Gut-Brain Axis the Missing Link?
Vitamin C's cognitive promise clashes with new clinical data
Liso-Cel Delivers Durable OS Benefit in R/R LBCL, Redefining Treatment
Get the full story11 min read
Arthritis PsoriaticFrailty, not just RA, predicts osteoporotic fracture risk
Get the full story6 min readEnpatoran gets breakthrough tag for lupus: Another IFN-I inhibitor enters the fray
Get the full story7 min readMicrobiome's Role in Lupus: A Policy and Therapeutic 'Frame Shift'
Get the full story10 min readSleep Disruption and Fear Drive Chronic Rheumatic Pain
Get the full story11 min readWhy Cheaper Humira Alternatives Face Resistance
Listen now22 minStopping Spinal Fusion Or Protecting The Gut?
Listen now23 minChasing Absolute Zero In Rheumatoid Arthritis
Listen now21 minThe ORAL Surveillance JAK Inhibitor Controversy
Listen now21 minB-Cell Dysregulation Targeted Upstream in Primary Sjögren Disease
Get the full story7 min readXLH Management: Rheumatology Must Adapt at EULAR 2026
Get the full story7 min read
Lung NeoplasmsCryoprobe Biopsy Improves Diagnostic Yield in Transbronchial Biopsy
Get the full story8 min readAir Embolism: Two Cases After Percutaneous Lung Biopsy
Get the full story7 min readSingle Question May Flag Poor Quality Sleep in Patients
Get the full story9 min readPembrolizumab Reduces Pulmonary AEs vs Chemotherapy in NSCLC
Get the full story8 min readDupilumab Superior to Omalizumab in High-Biomarker Asthma
Get the full story7 min readATS 2026: NTM Lung Disease Detection, Therapy, QoL Advancements
Get the full story8 min readBRINSUPRI® First Therapy Approved for NCFB at ATS 2026
Get the full story7 min readEpithelial Cytokines Link Severe Asthma, CRSwNP, COPD at ATS 2026
Get the full story8 min readTriple Therapy in Asthma: Real-World Evidence Supports Earlier Use
Get the full story7 min readYUTREPIA® (treprostinil) Inhalation Powder for PH-ILD Patients
Get the full story8 min readDrug Resistance MicrobialBundibugyo virus: Why community trust is the only vaccine we have
Get the full story11 min readInfluenza treatment: The single-dose option challenges multi-day adherence
Get the full story7 min readScrewworm EUA: How targeting larval development changes prevention
Get the full story7 min readTreating screwworm: Why an OTC generic is now the frontline
Get the full story6 min readThe antibiotic paradox: More drugs won't solve resistance
Get the full story10 min readMeningitis B: Why campus life shifts vaccine guidance for your patients
Get the full story6 min readBlack Death Survivors' Genetic Legacy Offers Clues for COVID-19 Resilience
Get the full story10 min readLong COVID: Objective Biomarkers Challenge Psychosomatic Narrative
Get the full story8 min readNew Virus Catalogue Identifies Top Pathogen Threats to Human Health
Get the full story7 min readSodium Fluoroacetate Offers Hope Against Australia's Mouse Plagues
Get the full story7 min read
Dermatitis AtopicPeptide Therapies: Decoding Evidence from Topicals to Longevity
Get the full story9 min readDermatomyositis Guidelines Identify Cancer Risk
Get the full story10 min readLitfulo Label Strengthened With New Alopecia Areata Safety Warnings
Get the full story8 min readFDA Rejects Galderma's RelabotulinumtoxinA for Second Time
Get the full story7 min readCAR T-Cell Therapy Nears Approval for Refractory Skin Diseases
Get the full story7 min readTSW Controversy: Mitochondrial NAD Excess Identified, Diagnostic Clarity Emerges
Get the full story9 min readPrior Authorization Delays Atopic Dermatitis Treatment Access
Get the full story13 min readPatient-Reported Factors Redefine Alopecia Areata Severity
Get the full story8 min readScalp Lesions: Rare Malignancies Mimic Benign Conditions
Get the full story7 min readDown Syndrome: Skin Conditions Demand Dermatologists’ Attention
Get the full story8 min read
• Aug 28 – 31ERS 2026 • Barcelona, ES 
• Sep 5 – 9EASD 2026 • Milan, IT 
• Sep 28 – Oct 2UEG Week 2026 • Vienna, AT 
• Oct 3 – 7Joint ACTRIMS-ECTRIMS 2026 • Toronto, CA 
• Oct 21 – 23ESMO 2026 • Madrid, ES • Oct 23 – 27AHA 2026 • Chicago, US 
• Nov 7 – 9ACR 2026 • Washington DC, US • Nov 14 – 19ASH 2026 • New Orleans, US • Dec 12 – 15ACC.27 Together With WCC • Houston, US • Apr 10 – 12ESC 2026 • Munich, DE • Aug 28 – 31ERS 2026 • Barcelona, ES • Sep 5 – 9EASD 2026 • Milan, IT • Sep 28 – Oct 2UEG Week 2026 • Vienna, AT • Oct 3 – 7Joint ACTRIMS-ECTRIMS 2026 • Toronto, CA • Oct 21 – 23ESMO 2026 • Madrid, ES • Oct 23 – 27AHA 2026 • Chicago, US • Nov 7 – 9ACR 2026 • Washington DC, US • Nov 14 – 19ASH 2026 • New Orleans, US • Dec 12 – 15ACC.27 Together With WCC • Houston, US • Apr 10 – 12
BostonJun 13 – 16 2026
XLH Adults: Osteomalacia Persists Despite Conventional Therapy
Adults with X-linked hypophosphatemia (XLH) frequently experience persistent osteomalacia, even with conventional phosphate and active vitamin D treatment.
Afirma Molecular Testing: Unique Situations and New Prognostic Development
Afirma molecular testing aids thyroid nodule management, particularly in indeterminate cytology. New prognostic markers enhance risk stratification.
GLP-1 RAs Reduce CV Risk in T2D Via Weight, Glucose Pathways
GLP-1 receptor agonists offer cardiovascular risk reduction in type 2 diabetes through both weight loss and direct glucose-lowering mechanisms.
Defining Hyperphagia Treatment Possibilities in Prader-Willi Syndrome
Clinician and caregiver perspectives highlight the complex challenges and unmet needs in managing hyperphagia in Prader-Willi Syndrome.
Liver-Directed Treatment Shows Efficacy in Metabolic Dysfunction
A novel liver-directed treatment presented at endo 2026 offers a targeted approach for metabolic dysfunction, addressing a significant unmet clinical need.
Hypoparathyroidism Treatment: Patient, Care Partner, HCP Perspectives
New perspectives on hypoparathyroidism treatment from patients, care partners, and HCPs highlight unmet needs and treatment goals.
Severe Hypoglycemia in T1D: Enhancing Patient-Clinician Dialogue
Addressing severe hypoglycemic events in type 1 diabetes requires direct, empathetic clinician-patient conversations to improve management and outcomes.
Endocrinologists' Role in Early Thyroid Eye Disease Recognition
Early recognition of thyroid eye disease (TED) by endocrinologists is critical for optimal patient outcomes, enabling timely intervention.
Classic CAH: New Approaches to Glucocorticoid Dosing
Endocrinology specialists are re-evaluating glucocorticoid dosing strategies for classic congenital adrenal hyperplasia (CAH), focusing on individualised regimens to balance androgen control and minimise adverse effects.
Low Alkaline Phosphatase: Recognizing Clinical Consequences
Low alkaline phosphatase (ALP) is often overlooked, but its clinical consequences, particularly hypophosphatasia, warrant increased diagnostic vigilance.
Desmopressin Dosing Refined for Central Diabetes Insipidus
New insights into desmopressin administration for central diabetes insipidus (CDI) aim to optimise efficacy and minimise hyponatremia risk.
Acromegaly Management: Focus on Biochemical Control at ENDO 2026
New insights from ENDO 2026 highlight the persistent challenges in achieving biochemical control for acromegaly patients.
12 Months of Romosozumab Builds Bone Density in Postmenopausal Osteoporosis
A 12-month course of romosozumab significantly increases bone mineral density in postmenopausal women with osteoporosis.
Desiccated Thyroid Extract: Efficacy and Safety in Hypothyroidism
A case-based discussion at endo 2026 reviewed the role of desiccated thyroid extract (DTE) in hypothyroidism management, highlighting patient selection and comparative efficacy.
Steroidogenesis Inhibitor Targets Root Cause of Cushing’s Syndrome
A novel steroidogenesis inhibitor presented at ENDO 2026 offers a targeted approach to endogenous Cushing's syndrome by reducing cortisol overproduction.
Peer Insights on Once-Daily Weight Management Therapy at endo 2026
Endocrinology specialists discussed the clinical utility of a once-daily treatment for weight management in appropriate adult patients.
Hypothyroidism: Symptom Burden Persists Despite Euthyroidism
Many patients with hypothyroidism report persistent symptoms despite achieving biochemical euthyroidism, highlighting a significant symptom-treatment gap.
Endo 2026: Risk-Based Osteoporosis Management Refines Clinical Practice
Endo 2026 highlighted refined risk-based strategies for osteoporosis care, advocating for tailored interventions beyond universal guidelines to improve patient outcomes.
Hypercortisolism: Emerging Diagnostic and Management Insights
New evidence presented at Endo 2026 refines our understanding of hypercortisolism, impacting diagnostic strategies and therapeutic approaches.
Obesity Care: Tailored Treatment Strategies Highlighted at endo 2026
Personalised treatment approaches for obesity, moving beyond a 'one-size-fits-all' model, were a key focus at endo 2026.
Cushing's Syndrome: Addressing Diagnostic Delays and Treatment Gaps
Cushing's syndrome presents a diagnostic challenge, often leading to significant delays in treatment initiation and suboptimal patient outcomes.
Korlym® for Cushing's Syndrome: Patient Experience, Side Effects and 2026 Clinical Data
Patient-reported outcomes from Endo 2026 show Korlym® (mifepristone) cuts weight gain, fatigue and mood disturbances in Cushing's syndrome. Covers mechanism of cortisol receptor blockade, side effect profile, and how it compares to relacorilant.
XLH Adults: Osteomalacia Persists Despite Conventional Therapy
Adults with X-linked hypophosphatemia (XLH) frequently experience persistent osteomalacia, even with conventional phosphate and active vitamin D treatment.
Afirma Molecular Testing: Unique Situations and New Prognostic Development
Afirma molecular testing aids thyroid nodule management, particularly in indeterminate cytology. New prognostic markers enhance risk stratification.
GLP-1 RAs Reduce CV Risk in T2D Via Weight, Glucose Pathways
GLP-1 receptor agonists offer cardiovascular risk reduction in type 2 diabetes through both weight loss and direct glucose-lowering mechanisms.
Defining Hyperphagia Treatment Possibilities in Prader-Willi Syndrome
Clinician and caregiver perspectives highlight the complex challenges and unmet needs in managing hyperphagia in Prader-Willi Syndrome.
Liver-Directed Treatment Shows Efficacy in Metabolic Dysfunction
A novel liver-directed treatment presented at endo 2026 offers a targeted approach for metabolic dysfunction, addressing a significant unmet clinical need.
Hypoparathyroidism Treatment: Patient, Care Partner, HCP Perspectives
New perspectives on hypoparathyroidism treatment from patients, care partners, and HCPs highlight unmet needs and treatment goals.
Severe Hypoglycemia in T1D: Enhancing Patient-Clinician Dialogue
Addressing severe hypoglycemic events in type 1 diabetes requires direct, empathetic clinician-patient conversations to improve management and outcomes.
Endocrinologists' Role in Early Thyroid Eye Disease Recognition
Early recognition of thyroid eye disease (TED) by endocrinologists is critical for optimal patient outcomes, enabling timely intervention.
Classic CAH: New Approaches to Glucocorticoid Dosing
Endocrinology specialists are re-evaluating glucocorticoid dosing strategies for classic congenital adrenal hyperplasia (CAH), focusing on individualised regimens to balance androgen control and minimise adverse effects.
Low Alkaline Phosphatase: Recognizing Clinical Consequences
Low alkaline phosphatase (ALP) is often overlooked, but its clinical consequences, particularly hypophosphatasia, warrant increased diagnostic vigilance.
Desmopressin Dosing Refined for Central Diabetes Insipidus
New insights into desmopressin administration for central diabetes insipidus (CDI) aim to optimise efficacy and minimise hyponatremia risk.
Acromegaly Management: Focus on Biochemical Control at ENDO 2026
New insights from ENDO 2026 highlight the persistent challenges in achieving biochemical control for acromegaly patients.
12 Months of Romosozumab Builds Bone Density in Postmenopausal Osteoporosis
A 12-month course of romosozumab significantly increases bone mineral density in postmenopausal women with osteoporosis.
Desiccated Thyroid Extract: Efficacy and Safety in Hypothyroidism
A case-based discussion at endo 2026 reviewed the role of desiccated thyroid extract (DTE) in hypothyroidism management, highlighting patient selection and comparative efficacy.
Steroidogenesis Inhibitor Targets Root Cause of Cushing’s Syndrome
A novel steroidogenesis inhibitor presented at ENDO 2026 offers a targeted approach to endogenous Cushing's syndrome by reducing cortisol overproduction.
Peer Insights on Once-Daily Weight Management Therapy at endo 2026
Endocrinology specialists discussed the clinical utility of a once-daily treatment for weight management in appropriate adult patients.
Hypothyroidism: Symptom Burden Persists Despite Euthyroidism
Many patients with hypothyroidism report persistent symptoms despite achieving biochemical euthyroidism, highlighting a significant symptom-treatment gap.
Endo 2026: Risk-Based Osteoporosis Management Refines Clinical Practice
Endo 2026 highlighted refined risk-based strategies for osteoporosis care, advocating for tailored interventions beyond universal guidelines to improve patient outcomes.
Hypercortisolism: Emerging Diagnostic and Management Insights
New evidence presented at Endo 2026 refines our understanding of hypercortisolism, impacting diagnostic strategies and therapeutic approaches.
Obesity Care: Tailored Treatment Strategies Highlighted at endo 2026
Personalised treatment approaches for obesity, moving beyond a 'one-size-fits-all' model, were a key focus at endo 2026.
Cushing's Syndrome: Addressing Diagnostic Delays and Treatment Gaps
Cushing's syndrome presents a diagnostic challenge, often leading to significant delays in treatment initiation and suboptimal patient outcomes.
Korlym® for Cushing's Syndrome: Patient Experience, Side Effects and 2026 Clinical Data
Patient-reported outcomes from Endo 2026 show Korlym® (mifepristone) cuts weight gain, fatigue and mood disturbances in Cushing's syndrome. Covers mechanism of cortisol receptor blockade, side effect profile, and how it compares to relacorilant.
