Do Condition-Specific Growth Charts Improve Care in Alagille Syndrome?

Growth charts tailored for Alagille Syndrome (ALGS) could refine the assessment of malnutrition in these children, but questions remain about their broad applicability. Clinicians should view these new charts cautiously, considering the limitations of the underlying data and the potential for misinterpretation.

Lorlatinib and Diabetic Ketoacidosis An Emerging Class Effect?

Patients on lorlatinib should be monitored for hyperglycemia, regardless of autoantibody status. This case raises concerns about potential metabolic toxicities of ALK inhibitors beyond what is currently recognized.

Optimizing Psychosocial Interventions for Adult Anxiety

Anxiety disorders require tailored approaches; one size rarely fits all. Evidence mapping now clarifies which psychosocial interventions demonstrate the most promise for specific adult anxiety profiles, allowing for more targeted treatment plans.

Infections in Ichthyosis: A Call for Vigilance

Patients with ALOX12B-associated autosomal recessive congenital ichthyosis face significant infectious risks beyond the skin. Clinicians should adopt proactive surveillance and management strategies, including early broad-spectrum antibiotics, to mitigate life-threatening complications.

Health Literacy and Lung Cancer Diagnostic Delays

Patients with limited health literacy experience significant delays in lung cancer diagnosis. This ultimately exacerbates existing health inequities and burdens the healthcare system.