Systemic Therapies for Atopic Dermatitis A Clinician's Guide
Atopic dermatitis management is evolving rapidly with new systemic therapies. This practical guide helps clinicians navigate the choice between biologics and JAK inhibitors, considering patient profiles and potential adverse effects.
Systemic Sclerosis and TB What to Watch For
Patients with systemic sclerosis, already vulnerable due to immunosuppression and lung involvement, face a heightened risk of pulmonary tuberculosis. This case highlights the diagnostic and therapeutic challenges when TB mimics or masks ILD progression.
Nanoparticles Boost Berberine's Antimicrobial Action in Root Canals
Berberine, a natural antimicrobial, shows enhanced potency against endodontic pathogens when delivered via polymeric nanoparticles. This targeted approach could improve root canal disinfection and reduce the need for aggressive chemical treatments.
Can AI Refine Primary Immune Dysregulation Diagnosis?
Machine learning offers a tantalizing opportunity to sub-classify primary immune dysregulation beyond current clinical capabilities. The question remains whether this computational approach will translate to improved patient outcomes or simply add another layer of complexity.
Erythroblasts in B12 Deficiency: An Ominous Sign?
The presence of early erythroblasts on peripheral blood film in severe vitamin B12 deficiency may indicate a more profound disruption of bone marrow function than previously appreciated. Clinicians should consider aggressive intervention and vigilant monitoring in such cases, as this presentation might signal a higher risk of complications.
