Automated IVUS processing for coronary anomalies: AIVUS-CAA

AIVUS-CAA targets automated intravascular ultrasound processing for coronary artery anomalies , combining segmentation and quantification to derive lumen, vessel, and plaque metrics. Benchmarked against expert annotations and reference measurements, the software reports high agreement and consistent border detection across varied image quality. Findings highlight methodological rigor, transparent definitions, and pathways for integration into analysis pipelines, with relevance for multicenter quantification and longitudinal research.

Spatial Transcriptomics Dissects Parkinson's Subtypes

Parkinson's disease and multiple system atrophy (MSA) can be difficult to distinguish clinically, leading to delayed or inappropriate treatment. A new spatial transcriptomics study offers a high-resolution view of gene expression patterns in the substantia nigra, potentially enabling more accurate diagnoses.

TAVI and Aortic Dissection Risk: Is Valve Type a Factor?

Delayed aortic dissection following TAVI remains a rare, but devastating, complication. The question is whether balloon-expandable valves present a unique biomechanical risk compared to self-expanding alternatives.

Cranial CT Scans Opportunistic Osteoporosis Screening Real World Policy Implications

Opportunistic osteoporosis screening using cranial CT scans could identify more patients at risk of major osteoporotic fractures. However, widespread implementation faces hurdles including medico-legal considerations and reimbursement complexities.

Depression Screening Policies in Chronic Care

Addressing depression in chronic care settings is vital for improving patient outcomes. Culturally relevant screening programs may optimize the identification of at-risk individuals and facilitate access to appropriate mental health services.