Parkinson's Neuroprotection 2025: Three Strategies Under Review

Stem cell therapy, System Xc- pathway modulation, and Ayurvedic add-on regimens are each being evaluated as neuroprotective strategies in Parkinson's disease.

PCSK9 Inhibitors Move Upstream: Evolocumab Tested in Diabetes Without Known Atherosclerosis

VESALIUS-CV tests evolocumab in diabetic patients without established atherosclerosis, while new trials probe plaque biology and lipid pathways beyond LDL.

TAVI and Aortic Dissection Risk: Is Valve Type a Factor?

Delayed aortic dissection following TAVI remains a rare, but devastating, complication. The question is whether balloon-expandable valves present a unique biomechanical risk compared to self-expanding alternatives.

Addiction Recovery: A Canadian Perspective on a Global Crisis

The Canadian Academy for Addiction Psychiatry (CAAP) highlights the urgent need for enhanced mental health and addiction treatment services, especially in the wake of the COVID-19 pandemic. Their commentary provides a framework that other countries might consider, although questions of scalability remain.

Atrial Fibrillation Complexity: How Reliable is Registry Data?

Patients with atrial fibrillation often present with a complex interplay of cardio-kidney-metabolic conditions, but large registry data can oversimplify these interactions. Clinicians should interpret such observational findings cautiously, especially when considering individual patient management.