Acne Recurrence: Can We Predict It?

Predicting acne recurrence remains challenging, impacting long-term management. A recent study proposes a nomogram for predicting recurrence, but its generalizability is questionable.

ADA2 Deficiency Atypical Presentation Requires Vigilance

Patients with early-onset neutropenia and unusual inflammatory symptoms should prompt consideration of Adenosine Deaminase 2 (ADA2) deficiency. Diagnosing this condition early can significantly alter treatment strategies and improve outcomes for affected children.

Systemic Therapies for Atopic Dermatitis A Clinician's Guide

Atopic dermatitis management is evolving rapidly with new systemic therapies. This practical guide helps clinicians navigate the choice between biologics and JAK inhibitors, considering patient profiles and potential adverse effects.

Spatial Transcriptomics Dissects Parkinson's Subtypes

Parkinson's disease and multiple system atrophy (MSA) can be difficult to distinguish clinically, leading to delayed or inappropriate treatment. A new spatial transcriptomics study offers a high-resolution view of gene expression patterns in the substantia nigra, potentially enabling more accurate diagnoses.

Do Vitamin D Supplements Improve Outcomes in Orthopedic Trauma?

Orthopedic trauma patients may experience improved fracture healing and reduced infection risk with vitamin D supplementation, suggesting a role in immune modulation. However, the existing evidence is not definitive enough to recommend universal supplementation.