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The Life Science Feed
Podcast
Deep dives with clinicians, researchers, and industry leaders.
All episodes
AI Enhances Oxygen Therapy Titration, Reduces Hypoxia Duration
Artificial intelligence algorithms are demonstrating efficacy in automating oxygen therapy titration, potentially reducing episodes of hypoxia and hyperoxia.
Virtual Team-Based GI Care Superior to Traditional Care
A virtual team-based care model for gastrointestinal conditions demonstrated superior patient outcomes and reduced healthcare utilisation compared to traditional care.
Alcohol and Sugar: A Dual Metabolic Challenge for Patients
Patients consuming alcohol and high-sugar diets face a compounded metabolic risk, impacting liver function and glucose regulation. Clinicians must address both factors.
Immunotherapy and Targeted Therapy: New Data from ASCO 2026
New research from ASCO 2026 explores combination strategies for advanced cancers and a machine learning approach to immunotherapy target discovery.
Endo 2026: Risk-Based Osteoporosis Management Refines Clinical Practice
Endo 2026 highlighted refined risk-based strategies for osteoporosis care, advocating for tailored interventions beyond universal guidelines to improve patient outcomes.
BTK Inhibitors in CLL: Evolving Landscape and Sequential Strategies
The management of chronic lymphocytic leukemia (CLL) with BTK inhibitors is evolving, necessitating careful consideration of treatment sequencing and resistance mechanisms.
Reassuring Data for High-Efficacy MS Meds in Pregnancy
New data provide reassurance regarding the use of high-efficacy multiple sclerosis therapies during pregnancy, addressing a significant clinical dilemma.
Psoriasis Patients Report Chronic Intense Pain, Multiple Pain Sites
Psoriasis is associated with chronic intense pain and a higher prevalence of multiple pain sites, impacting patient quality of life.
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Life Science.
Belzutifan Plus Pembrolizumab Approved for Adjuvant RCC
The FDA has approved belzutifan plus pembrolizumab for adjuvant renal cell carcinoma, offering a new option for patients at high risk of recurrence.
ctDNA Predicts Relapse in Early Cancer, but Clinical Action Remains Unclear
Circulating tumour DNA (ctDNA) detection post-surgery predicts relapse in early-stage cancer, but evidence for adjuvant therapy escalation based solely on ctDNA is lacking.
PROTEUS Trial: Neoadjuvant Apalutamide Plus ADT in High-Risk Prostate Cancer
The PROTEUS trial investigated neoadjuvant apalutamide plus ADT for high-risk localised prostate cancer, showing improved pathologic complete response rates.
CAR-T Therapy Versus Bispecific Antibodies
24 minSmall Molecules VS CAR-T In CLL
23 minMoving CAR-T To Earlier Myeloma Lines
24 minCAR-T Masterstroke Or Biological Chaos?
22 minDoctor-Patient Communication Improves Treatment Acceptance in Cancer
6 min readTile Radiation for Large Brain Mets: A New Approach at ASCO 2026
6 min readAlcohol and Sugar: A Dual Metabolic Challenge for Patients
Patients consuming alcohol and high-sugar diets face a compounded metabolic risk, impacting liver function and glucose regulation. Clinicians must address both factors.
EASL Congress 2026: Key Trials to Watch in Liver Disease Management
EASL Congress 2026 will feature pivotal trials in NAFLD/NASH, HBV, and HCC, potentially reshaping current treatment paradigms.
Variceal Bleeding Management: EASL 2026 Skills Centre Focuses on Endoscopic and Pharmacological Strategies
EASL 2026 Skills Learning Centre will address variceal bleeding, highlighting current evidence for endoscopic and pharmacological interventions.
EASL 2026: Liver and Spleen Elastography for Fibrosis Assessment
6 min readEASL 2026 Forum: Enhancing Patient-Clinician Communication
6 min readEASL 2026: Alcohol Policy Action Needed for Liver Disease
6 min readA-TANGO Score Refines ACLF Diagnosis, Prognosis in Cirrhosis
6 min readMASLD Diagnosis Faces Barriers Despite 2024 EASL Guidelines
5 min readEASL 2026: Non-invasive Diagnostics Advance Liver Disease Staging
7 min read
Zurich Heart Surgery Scandal: Device Safety Alert Issued
A safety alert has been issued regarding cardiac devices used in Zurich, prompting concerns about patient outcomes and regulatory oversight.
Serum Potassium Concentrations Shape Heart Failure Risk
Optimal serum potassium concentrations in heart failure (HF) are unclear, with new data clarifying the safe range for HFrEF and HFpEF.
Managing Acute Heart Failure And Cardiogenic Shock
Acute decompensated heart failure drives over one million hospital admissions annually. 30-day readmission rates are 25%. When the heart cannot compensate, the tools change entirely - IV diuretics, inotropes, mechanical circulatory support. Sarah Mitchell and James Carter cover ADHF management, cardiogenic shock, and how to prevent the revolving door.
Semaglutide For Obese Heart Failure Patients
21 minDiabetes Drugs For Stiff Heart Failure
21 minHow Four Drugs Beat Heart Failure
22 minTricuspid Valve Surgery Benefits Adults with Systemic Right Ventricle
6 min readDual Plane Block May Cut Opioid Use After Bypass Surgery
6 min readPAHO's HEARTS 2.0 Outlines 38-Step Pathway for Cardio-Renal Care
6 min read
GLP-1 Agonists and Ischemic Optic Neuropathy: A Review
GLP-1 receptor agonists are widely used for type 2 diabetes and weight management. Recent data suggests a potential association with ischemic optic neuropathy.
GLP-1 Weight Regain: Emerging Strategies to Sustain Loss
Strategies are emerging to mitigate weight regain post-GLP-1 receptor agonist discontinuation, focusing on sustained pharmacological intervention.
Retatrutide Shows 24.2% Weight Reduction in Phase II Trial
A Phase II trial of retatrutide demonstrated substantial weight loss and improvements in cardiometabolic markers in adults with obesity.
OTC CGM Approved for Paediatric Diabetes Management
7 min readOral GLP-1 Analogues Show A1c Reduction, Weight Loss at ADA 2026
7 min readObesity Care: Tailored Treatment Strategies Highlighted at endo 2026
6 min readHypercortisolism: Emerging Diagnostic and Management Insights
7 min read12 Months of Romosozumab Builds Bone Density in Postmenopausal Osteoporosis
7 min readCushing's Syndrome: Addressing Diagnostic Delays and Treatment Gaps
6 min read
Preventing 45 Percent Of Dementia Cases
The Lancet Commission 2024 estimates 45% of dementia is preventable. SPRINT-MIND showed 19% MCI reduction from intensive blood pressure control. FINGER showed 25% better cognitive scores with multi-domain lifestyle intervention. ACHIEVE showed 48% slowing in high-risk patients with hearing aids. The evidence is here — we walk through it.
Targeting Tau Inflammation And Alzheimer's Metabolism
Amyloid clearance is only one part of the Alzheimer's story. Why tau remains the closer correlate of cognitive decline, what the TREM2 biology tells us about microglia, what the GLP-1 signal means, and how platform trials are moving toward multi-target combination therapy.
Why New Alzheimer's Drugs Make Brains Bleed?
ARIA — amyloid-related imaging abnormalities — affects up to 24% of patients on anti-amyloid therapy. APOE4 genotyping, MRI monitoring protocols, severity-graded management, and the anticoagulation dilemma: a practical guide to navigating the risk.
The Amyloid Hypothesis, Finally Validated?
39 minCGRP Monoclonal Antibodies for Migraine Linked to Fracture Risk
6 min readReassuring Data for High-Efficacy MS Meds in Pregnancy
6 min readAmyloid Therapies Show Limited Cognitive Benefit in Alzheimer's
7 min readCGRP Inhibitors for Migraine: CV Safety Data Limited in High-Risk Patients
5 min readAmyloid Therapies Show Limited Cognitive Benefit in AD
4 min read
