Opportunistic Osteoporosis Screening from CT Scans A Validated Approach?

Using cranial CT scans for opportunistic osteoporosis screening shows promise, but concerns remain. Addressing methodological criticisms is essential for validating this approach in broader clinical practice.

TAVI and Aortic Dissection Risk: Is Valve Type a Factor?

Delayed aortic dissection following TAVI remains a rare, but devastating, complication. The question is whether balloon-expandable valves present a unique biomechanical risk compared to self-expanding alternatives.

Dextromethorphan Anaphylaxis Pharmacovigilance Gaps

A recent case report highlights a rare instance of anaphylaxis to dextromethorphan (DXM), a common over-the-counter cough suppressant. This raises concerns about the adequacy of current pharmacovigilance systems for OTC medications and the potential for underreporting of hypersensitivity reactions.

Nanoparticles Boost Berberine's Antimicrobial Action in Root Canals

Berberine, a natural antimicrobial, shows enhanced potency against endodontic pathogens when delivered via polymeric nanoparticles. This targeted approach could improve root canal disinfection and reduce the need for aggressive chemical treatments.

SGLT2 Inhibitors: Promise and Peril in Prader-Willi Syndrome?

SGLT2 inhibitors show potential for managing glycemic control in Prader-Willi Syndrome, but clinicians must be vigilant about the risk of renal complications. This necessitates careful patient selection and close monitoring of kidney function throughout treatment.