Rheumatology

Sleep Disruption and Fear Drive Chronic Rheumatic Pain

Poor sleep and fear avoidance behaviors are significant, often overlooked, drivers of chronic rheumatic pain, necessitating integrated management strategies.

Why Cheaper Humira Alternatives Face Resistance

Humira (adalimumab) biosimilar alternatives have cut NHS spend by over 50% while expanding treatment access. Evidence from NOR-SWITCH confirms switching is safe, yet resistance persists, driven by the nocebo effect and physician inertia.

Stopping Spinal Fusion Or Protecting The Gut?

PsA is not RA with skin, and axSpA is not RA in the spine. The biologic hierarchy shifts significantly across the spondyloarthropathy spectrum - IL-17 and IL-23 inhibitors dominate, anti-TNF has uveitis caveats, and IBD comorbidity changes everything. Sarah...

Chasing Absolute Zero In Rheumatoid Arthritis

Treat-to-target transformed RA outcomes - not through new drugs but through rigorous measurement and escalation discipline. Sarah Mitchell and James Carter cover the evidence base, the disease activity tools, the window of opportunity in early RA, and when ...

The ORAL Surveillance JAK Inhibitor Controversy

ORAL Surveillance showed tofacitinib carried higher cardiovascular and malignancy risk than anti-TNF in high-risk RA patients - triggering a class-wide boxed warning. But was the signal overgeneralised? Sarah Mitchell and James Carter unpack the data, the c...

B-Cell Dysregulation Targeted Upstream in Primary Sjögren Disease

New research presented at EULAR 2026 explores upstream B-cell targeting to address primary Sjögren disease pathology, focusing on early intervention.

XLH Management: Rheumatology Must Adapt at EULAR 2026

Current rheumatology approaches for rare bone diseases like X-linked hypophosphatemia (XLH) require re-evaluation. EULAR 2026 presents an opportunity to integrate multidisciplinary care models.

EGPA: Early Recognition & Targeted Intervention Improve Outcomes

Eosinophilic granulomatosis with polyangiitis (EGPA) presents diagnostic challenges; timely intervention is critical for improved patient outcomes.

RA Patients Face Elevated Fracture Risk: EULAR 2026 Highlights

Rheumatoid arthritis (RA) significantly increases fracture risk beyond traditional factors. EULAR 2026 data underscores the need for early bone health assessment.