Choosing the optimal revascularization strategy for iliac occlusive disease remains a challenge. We face a spectrum of options, from open surgical bypass to endovascular techniques like angioplasty and stenting. The key question isn't just which method works, but which works best for *whom*, and under what circumstances. A recent comparative review offers some clarity, distilling a decade of experience into actionable insights for revascularization decision-making. But how does it align with existing guidelines, and are there catches we should be aware of?

This isn't simply about adopting the newest gizmo. It's about patient selection, anatomical considerations, and understanding the long-term implications of each approach. Do the findings truly shift the paradigm, or are they merely a refinement of existing practice?

Clinical Key Takeaways

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  • The PivotThis review highlights that for complex aortoiliac lesions (TASC C/D), surgical bypass still offers durable patency, challenging the complete dominance of endovascular approaches.
  • The DataPrimary patency rates for surgical bypass at 5 years often exceed those of endovascular therapy in TASC C/D lesions, sometimes by 10-20%.
  • The ActionWhen faced with extensive aortoiliac disease, discuss surgical options with your patient, even if you are an endovascular specialist. Don't reflexively default to the perceived less invasive approach.

Current Guidelines and Divergences

Major vascular surgery guidelines, such as those from the Society for Vascular Surgery (SVS) and the European Society for Vascular Surgery (ESVS), generally advocate for an endovascular-first approach in most cases of iliac occlusive disease. This stems from the lower initial morbidity and mortality associated with endovascular procedures compared to open surgery. However, these guidelines also acknowledge that open surgical bypass remains the gold standard for complex aortoiliac lesions, particularly those classified as TASC C or D. The present review's findings don't necessarily contradict these guidelines but emphasize the need for careful patient selection and a nuanced understanding of lesion morphology. Are we truly weighing the long-term patency of surgical bypass against the less invasive nature of endovascular options with sufficient rigor? Or are we, perhaps, too quick to default to the latter?

Endovascular as First-Line: The Nuances

Endovascular techniques, including angioplasty with or without stenting, have revolutionized the treatment of iliac occlusive disease. They offer the advantage of smaller incisions, shorter hospital stays, and quicker recovery times. For TASC A and B lesions, endovascular therapy demonstrates excellent long-term patency rates. However, for more complex TASC C and D lesions, the long-term outcomes are less predictable. The review suggests that in these complex cases, the pursuit of a less invasive approach may compromise long-term patency and increase the need for re-interventions. The question then becomes: at what point does the cumulative morbidity of repeated endovascular procedures outweigh the initial risk of open surgery?

Surgical Bypass: Still Relevant for Complex Cases

Despite the rise of endovascular therapy, open surgical bypass remains a durable and effective option for complex aortoiliac disease. Aortobifemoral bypass, in particular, provides excellent long-term patency, often exceeding that of endovascular approaches for TASC C and D lesions. The review reinforces this point, highlighting the importance of considering surgical bypass in patients with extensive disease, those who have failed previous endovascular interventions, or those with specific anatomical challenges that preclude successful endovascular treatment. What is *your* threshold for considering surgical intervention? Have you honestly assessed your own comfort level and expertise with open techniques, or are you implicitly biased toward the tools you use most frequently?

Limitations of the Data

It's crucial to acknowledge the limitations inherent in any literature review, particularly one spanning a decade. Technological advancements in endovascular devices and techniques have occurred rapidly during this period, potentially making older data less relevant. Furthermore, the review relies on observational studies and retrospective analyses, which are subject to selection bias and confounding variables. There's also the issue of heterogeneity across studies in terms of patient populations, lesion characteristics, and definitions of success. Finally, who funded these studies? Were they supported by industry, which might introduce a bias toward promoting specific devices or techniques?

Economic Considerations

The economic implications of choosing between endovascular and surgical revascularization are significant. Endovascular procedures typically have higher upfront costs due to the expense of devices such as stents and balloons. However, the shorter hospital stays and quicker recovery times associated with endovascular therapy may offset these initial costs. Surgical bypass, on the other hand, has lower device costs but requires longer hospital stays and may be associated with higher rates of complications, leading to increased overall costs. Furthermore, reimbursement rates for these procedures vary depending on the payer and geographic location, adding another layer of complexity to the economic equation. Are hospitals incentivized to favor one approach over another based on reimbursement structures, even if it's not necessarily in the best interest of the patient?

The practical implication of this review is a call for more individualized decision-making in the treatment of iliac occlusive disease. Clinicians should carefully assess the patient's overall health, the severity and complexity of the lesion, and the available resources and expertise before selecting a revascularization strategy. A multidisciplinary approach, involving vascular surgeons, interventional radiologists, and cardiologists, is essential to ensure that each patient receives the most appropriate and effective treatment. Consider that your choice affects not only immediate patient outcomes but also resource allocation and hospital finances.

Implementing a standardized protocol for assessing iliac lesions, including detailed angiographic imaging and TASC classification, could help to improve patient selection and optimize outcomes. Furthermore, tracking long-term patency rates and re-intervention rates for both endovascular and surgical approaches is crucial for ongoing quality improvement and refinement of treatment strategies. We must be vigilant in monitoring the real-world performance of these techniques, not just relying on idealized results from clinical trials.

LSF-8618622238 | January 2026

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Ross MacReady
Ross MacReady
Pharma & Policy Editor
A veteran health policy reporter who spent 15 years covering Capitol Hill and the FDA. Ross specializes in the "business of science", tracking drug pricing, regulatory loopholes, and payer strategies. Known for his skepticism and deep sourcing within the pharmaceutical industry, he focuses on the financial realities that dictate patient access.
How to cite this article

MacReady R. Iliac revascularization: when to choose what?. The Life Science Feed. Published February 23, 2026. Updated February 23, 2026. Accessed February 23, 2026. https://thelifesciencefeed.com/cardiology/peripheral-arterial-disease/practice/iliac-revascularization-when-to-choose-what.

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References
  • Society for Vascular Surgery. (2015). SVS guidelines for management of peripheral arterial disease. Journal of Vascular Surgery, 61(3S), 1S-314S.
  • Aboyans, V., Ricco, J. B., Bartelink, M. L., Björck, M., Brodmann, M., Cohnert, T., ... & Tendera, M. (2017). 2017 ESC Guidelines on the Diagnosis and Treatment of Peripheral Arterial Diseases, in collaboration with the European Society for Vascular Surgery (ESVS): Document supported by: the European Society for Cardiology (ESC). European Heart Journal, 39(9), 763-816.
  • Gerhard-Herman, M. D., Gornik, H. L., Barrett, C., Hiatt, W. R., Jaff, M. R., Mohler, E. R., ... & Treat-Jacobson, D. (2016). 2016 AHA/ACC guideline on the management of patients with lower extremity peripheral artery disease: a report of the American Heart Association/American College of Cardiology Task Force on Clinical Practice Guidelines. Circulation, 135(12), e726-e779.
  • здійснює, N., ОПЕРАТИВНЕ ВТРУЧАННЯ У ВІДДІЛЕННІ, П., ТА, М., ХІРУРГІЧНІ. (2023). Endovascular versus open surgical revascularization for chronic iliac artery occlusive disease: A systematic review and meta-analysis. Annals of Medicine and Surgery, 93, 105145.
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