insights

Identifying patients at high risk for irreversible sudden sensorineural hearing loss demands a deeper look at factors beyond initial hearing thresholds. Clinicians must consider early indicators like vertigo and advanced age as potential markers of broader ...

Patients with shoulder pain from supraspinatus tendinopathy often face limited effective treatment options. This review challenges the outdated inflammatory model, positioning shockwave therapy as a mechanobiological intervention aligned with current unders...

Rare disease research offers an untapped reservoir of insights, potentially reshaping how we understand and treat pediatric rheumatology . Integrating multi-omics approaches could redefine diagnostic precision and therapeutic strategies for complex diseases.

Immune thrombocytopenia is associated with bleeding and infection risk, yet long-term mortality patterns remain heterogeneous. A 24-year U.S. analysis mapped trends and disparities by age, sex, race and comorbidity, highlighting higher-risk subgroups. Findi...

In India, quasi-experimental analyses of health insurance expansion and cardiometabolic risk examined blood pressure, glycemia, and adiposity. Coverage improved financial protection but showed limited and heterogeneous shifts in risk-factor levels over shor...

Cardiology prescribing of PCSK9 inhibitors, ARNi, and DOACs was examined by linking the NCDR PINNACLE registry with the Open Payments program. Payments to physicians correlated with higher use of these newer, higher-cost therapies, with associations varying...

In cardiac magnetic resonance mapping, native T1 and synthetic extracellular volume appear sensitive to age and sex, indicating that demographic context influences quantitative interpretations. Across routine clinical parameters, signal behavior varied in w...

Elderly displacement intersects with frailty and multimorbidity, shaping healthcare use through disrupted continuity of care . In Israel, older Ukrainian arrivals showed concentrated primary care contact and medication renewal, indicating chronic disease ma...

In severe aortic regurgitation, a cardiac damage staging framework originally developed for aortic stenosis appears to stratify the chance of left ventricular reverse remodeling after intervention. By indexing extra-valvular involvement and cumulative myoca...

In ST-elevation myocardial infarction, selective removal of circulating C-reactive protein targets a downstream inflammatory effector implicated in complement activation and opsonization of injured myocardium. A randomized trial will test whether lowering C...