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Achieving 'normalization' in hemophilia care, while improving patient outcomes, introduces substantial financial burdens on healthcare systems. Payers must grapple with the high costs of novel therapies and ensure equitable access.

The concept of 'normalization' in hemophilia care shifts the focus from merely preventing bleeds to enabling patients to live full, unrestricted lives. Clinicians need to proactively address lifestyle goals, activity levels, and psychosocial well-being in a...