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Urinary exosomes offer a non-invasive route to understanding kidney health, potentially surpassing traditional urine protein measurements. This innovation could lead to earlier and more precise diagnoses of various kidney diseases .
Urinary exosomes hold promise for early kidney disease detection, but significant validation is needed. Premature clinical adoption could lead to misdiagnosis and inappropriate treatment.
The decline in urine microscopy impacts diagnostic accuracy and potentially increases healthcare costs due to reliance on automated, less informative tests. Addressing systemic barriers, such as inadequate reimbursement and training, is essential for preser...
In an era of automated urine analysis, critical diagnostic information can be missed. A focused look at the urine sediment may reveal the key to unlocking a diagnostic puzzle, especially when algorithms fail.
Artificial intelligence offers a tantalizing promise: to predict transplant rejection and optimize immunosuppression, potentially expanding access to kidney transplantation . But substantial validation is needed before widespread implementation.
Digital transformation in nephrology and transplantation promises improved outcomes, but inequities in access could worsen outcomes for vulnerable populations. Healthcare systems must consider the financial and logistical burdens associated with implementin...
Cystatin C, a filtration biomarker less influenced by muscle mass than creatinine, was associated with 20-year all-cause and cardiovascular mortality in a nationally representative US cohort. Associations persisted after adjustment for demographics, comorbi...
Cystatin C, an alternative filtration marker for kidney function, was associated with long-term all-cause and cardiovascular mortality in a general US cohort over 20 years, independent of demographics, comorbidities, and creatinine-based eGFR. The results s...
In a general US cohort, higher baseline cystatin C, a filtration biomarker independent of muscle mass, tracked with increased all-cause and cardiovascular mortality over 20 years. Associations persisted after adjustment for creatinine-based eGFR and risk fa...
Chronic kidney disease risk assessment is evolving as cystatin C, a filtration marker less affected by muscle mass than creatinine, shows a persistent association with 20-year all-cause and cardiovascular mortality in a representative US cohort. The signal ...