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Brief CBT Workshop Reduces Anxiety, Boosts Grit in Primary Students

A brief cognitive behavioral therapy workshop significantly reduced anxiety and improved active coping strategies and grit among primary school students in Malaysia.

Peptide Therapies: Decoding Evidence from Topicals to Longevity

Peptide therapies show varied efficacy across indications, from established dermatological uses to investigational longevity applications. Clinicians must scrutinise the evidence for each specific peptide.

26 States Sue to Block Medicaid Work Requirements, Citing Access Concerns

A coalition of 26 states filed suit to prevent the implementation of Medicaid work requirements, arguing the policy jeopardizes healthcare access for vulnerable populations.

Obamacare Enrollment Shrinks in Many States, Federal Data Shows

New federal data reveals a significant decrease in Obamacare enrollment across numerous states over the past year, impacting access to health coverage.

ACA Insurers Seek Higher Premiums Amid Enrollment Decline

Affordable Care Act insurers are requesting substantial premium increases for 2025, citing a decline in enrollment and rising healthcare costs.

Leapfrog Group's Legal Defeat Underscores Hospital Quality Rating Challenges

A recent court ruling against the Leapfrog Group highlights the significant hurdles in accurately and fairly rating hospital quality, raising questions about current methodologies.

Dana-Farber CEO Details Split from Mass General Brigham, New Hospital Plans

Dana-Farber Cancer Institute CEO Laurie Glimcher outlined plans for an independent future, including a new cancer hospital, following its separation from Mass General Brigham.

Judge Temporarily Blocks Subpoenas in NY Transgender Care Probe

A New York judge temporarily blocked subpoenas seeking patient records in a criminal probe of transgender care at two hospitals, citing patient privacy concerns.

NIH diversity programs doubled PhD odds for undergraduates, 20-year study finds

NIH-funded diversity programs significantly increased the likelihood of undergraduates earning a PhD, doubling their odds over two decades.

Next-Gen CRISPR Improves Embryo Editing Accuracy, Stoking Ethical Debate

Advanced CRISPR tools enhance precision in human embryo gene editing, reducing off-target effects but intensifying ethical concerns over germline modification.

Synthetic Cell Raises Fundamental Questions About Life's Definition

Researchers have created a synthetic cell capable of self-replication, challenging established biological definitions of life and raising ethical considerations.

FDA Clears LLM for Triage: Interface or Decision-Maker?

The FDA cleared an LLM for acute pancreatitis triage, raising questions about its role as an interface versus a primary decision-maker in clinical settings.

AI Regulator: Biopharma Misinterprets FDA Guidance on Machine Learning

A former FDA AI regulator states biopharma companies are misreading agency guidance, potentially hindering AI adoption in drug development and clinical trials.

Online GLP-1 Prescriptions Often Lack Clinical Oversight

Rapid online GLP-1 prescriptions frequently bypass essential clinical assessments, raising concerns about patient safety and appropriate use.

Congressman Kean Jr. Reveals Depression Diagnosis After Absence

Representative Tom Kean Jr. disclosed a depression diagnosis following a four-month absence from Congress, highlighting the prevalence of mental health conditions.

GOP Lawmakers Push FDA on Clinical Trial Diversity

Republican lawmakers are pressing the FDA to enforce greater diversity in clinical trials, citing concerns over health equity and drug efficacy across varied populations.

Trump Administration Seeks Durable Science Policy Changes After Court Setbacks

The Trump administration is pursuing more lasting alterations to federal science policy, shifting focus to regulatory changes after previous court challenges.

Presidential Fitness Test: A Step, Not a Solution for Public Health

The new presidential fitness test offers a positive step toward promoting physical activity but falls short as a comprehensive public health strategy, experts contend.

Diarrhea Parasite Outbreak Exceeds 1,000 Cases Across Europe

A widespread outbreak of a diarrhea-causing parasite has surpassed 1,000 confirmed cases, prompting public health warnings across several European nations.

Ebola in Congo: Global Response Capacity Disappears Amidst Conflict

The ongoing Ebola outbreak in the Democratic Republic of Congo highlights critical failures in global health response, exacerbated by conflict and resource diversion.

Ebola Outbreaks Demand Swift, Coordinated Public Health Response

Former CDC Chief Tom Frieden emphasizes the critical need for rapid, coordinated public health interventions to contain Ebola outbreaks, highlighting lessons from past epidemics.

COVID Vaccine Efficacy Wanes, Boosters Essential for Sustained Protection

Initial COVID-19 vaccine efficacy significantly declines over several months, necessitating booster doses to maintain robust protection against infection and severe disease.

Men Face Later Cancer Diagnoses Across 20 Types

Men are more likely to receive a later-stage cancer diagnosis across 20 different cancer types, leading to worse prognoses and treatment outcomes.

600 Dead in Outbreak; Obamacare Now Trumpcare? Rare Cancer Cluster in Kids

A severe outbreak has claimed 600 lives, while policy shifts threaten healthcare access. A rare pediatric cancer cluster raises urgent public health concerns.

CDC Reverses Chickenpox Vaccine Guidance, Impacting Pediatricians and Public Health

The CDC has reversed its stance on chickenpox vaccine recommendations, shifting from universal childhood vaccination to a more targeted approach for specific risk groups.

Diarrhea Surges in Quake-Hit Venezuela Amid Humanitarian Crisis

A significant increase in diarrheal diseases is impacting Venezuela's earthquake-affected regions, exacerbating an already dire humanitarian situation.

Earthquake Aftermath: Clinical Priorities for GPs and Specialists

Immediate clinical priorities following an earthquake include crush injury management, infection prevention, and mental health support for survivors.

Haaland's 6,000-Calorie Diet: Performance Fuel or Health Risk?

Erling Haaland's reported 6,000-calorie daily diet, while fueling elite athletic performance, presents significant long-term health considerations for the general population.

Bowhead Whale Longevity Genes Offer Clues for Cancer, Aging

Insights from the bowhead whale's exceptional lifespan and cancer resistance point to novel genetic pathways for human anti-aging and oncology research.

Chatbots Disrupt Medical Education and Patient Information Seeking

Generative AI presents a disruption to medical education and healthcare delivery on par with the Flexner Report, influencing patient trust and information seeking.

Universal Heart Failure Definition Issued by Global Societies

Four major cardiology societies released a universal definition of heart failure, aiming to standardise diagnosis and research across the globe.

Dopamine Agonists: A Fading Role in Parkinson's Treatment?

Dopamine agonists, once a cornerstone for Parkinson's disease, face increasing scrutiny due to neuropsychiatric side effects and limited long-term motor benefits.

Low Support, High Fear Hinder Opioid Substitution Withdrawal Success

Patients attempting medically supervised withdrawal from opioid substitution therapy face significant barriers, with fear of withdrawal symptoms and inadequate social support driving high rates of treatment discontinuation.

Prostate Care: Balancing Immediate Relief with Long-Term Retreatment

Managing benign prostatic hyperplasia requires weighing rapid symptom improvement against the need for future interventions. Clinicians must consider patient preference and disease progression.

Liso-Cel Delivers Durable OS Benefit in R/R LBCL, Redefining Treatment

Lisocabtagene maraleucel (liso-cel) significantly extended overall survival in relapsed/refractory large B-cell lymphoma, establishing a new benchmark for second-line therapy.

Isaacs Emphasizes 'Human Touch' in Diabetes Care Beyond Technology

Diana Isaacs, PharmD, an ADA award winner, advocates for integrating empathetic, patient-centered approaches with advanced diabetes technology to improve outcomes.

Medically Tailored Meals Cut HbA1c More Than Subsidies in Type 2 Diabetes

Medically tailored meals reduced HbA1c by 0.59% more than food subsidies in patients with type 2 diabetes, demonstrating superior glycemic control.

Eptinezumab Improves Cognitive Symptoms in Migraine Patients

Eptinezumab significantly reduced cognitive symptoms in patients with migraine, offering a new dimension of relief beyond headache frequency.

Migraine Linked to Increased Vascular Dementia Odds in Observational Data

Observational studies indicate a consistent association between a history of migraine and elevated odds for developing vascular dementia later in life.

MIGS Integration in Cataract Surgery Improves IOP Control

Integrating minimally invasive glaucoma surgery (MIGS) with cataract extraction offers superior intraocular pressure control for patients with coexisting glaucoma.

Xiidra Leads Most Patients to 'Clinically Meaningful' Eye Dryness Reduction

Lifitegrast (Xiidra) significantly reduced eye dryness symptoms in a majority of patients with dry eye disease, offering a new therapeutic option.

FDA Approves Immgolis, First Golimumab Biosimilar for UC and RA

The FDA approved Immgolis, a golimumab biosimilar, for multiple inflammatory conditions including ulcerative colitis and rheumatoid arthritis, offering a new treatment option.

Co-antibody combination tops golimumab, guselkumab in refractory IBD

A novel co-antibody combination therapy demonstrated superior efficacy over existing biologics, golimumab and guselkumab, in patients with refractory inflammatory bowel disease.

Upadacitinib, Infliximab Lead for Rapid Ulcerative Colitis Relief

Upadacitinib and infliximab emerge as frontrunners for rapid clinical response in ulcerative colitis, offering quicker symptom resolution than other biologics.

Genetic Biomarker Predicts Adverse Outcomes in IBD

A specific genetic biomarker is linked to increased risk of adverse outcomes, including surgery and hospitalisation, in both ulcerative colitis and Crohn's disease.

CMS Prior Authorization Reforms Commendable, Still Needs Work, ACR Says

CMS's new rule reforming prior authorization aims to streamline processes, but the American College of Rheumatology states it does not go far enough to reduce clinician burden.

Medicare Exclusions: Avoiding Boring Mistakes That Cost Practices

Minor administrative errors and compliance oversights can lead to Medicare exclusion, severely impacting a practice's financial viability and patient access.

FDA Advisory Committee on Peptides Riddled with Conflicts of Interest

An FDA advisory committee reviewing peptide therapies for obesity included members with significant financial ties to drug manufacturers, raising concerns about impartiality.