Diabetes Drugs For Stiff Heart Failure

Managing Acute Heart Failure And Cardiogenic Shock

Acute decompensated heart failure drives over one million hospital admissions annually. 30-day readmission rates are 25%. When the heart cannot compensate, the tools change entirely - IV diuretics, inotropes, mechanical circulatory support. Sarah Mitchell and James Carter cover ADHF management, cardiogenic shock, and how to prevent the revolving door.

Semaglutide For Obese Heart Failure Patients

More than 80% of HFpEF patients are overweight or obese. STEP-HFpEF showed semaglutide 2.4mg improved symptoms by 16 points on the KCCQ and reduced weight by 13.3% - now a Class IIa ESC recommendation. Sarah Mitchell and James Carter explore why treating the metabolic environment is the new paradigm for HFpEF.

How Four Drugs Beat Heart Failure

Four drug classes — ARNi, beta-blocker, MRA, SGLT2 inhibitor — have together produced a 73% reduction in cardiovascular death and hospitalisation versus placebo in HFrEF. Sarah Mitchell and James Carter unpack why each drug works, what the landmark trials showed, and why clinical inertia is still the biggest barrier to optimal care.

Tricuspid Valve Surgery Benefits Adults with Systemic Right Ventricle

Adults with transposition of the great arteries (TGA) and systemic morphologic right ventricle (SRV) often develop SRV failure and tricuspid regurgitation (TR). A new study investigates the impact of tricuspid valve surgery (TVS) on clinical outcomes in this population.