
Recurrent UTIs in women: What works when antibiotics are no longer enough?
New strategies are emerging for recurrent urinary tract infections in women, moving beyond antibiotics to address persistent symptoms and reduce recurrence rates.
Gepotidacin: A New Oral Option for Uncomplicated UTIs in Adolescents
Gepotidacin, a first-in-class oral antibiotic, received approval in 2025 for uncomplicated UTIs in female patients aged 12 years and older and weighing at least 40 kg.
When minimally invasive BPH therapies fail, what's next?
Minimally invasive surgical therapies for BPH offer sexual function preservation, but retreatment rates vary. Repeat MIST is feasible for BPH recurrence.
BPH treatment: The sexual side effects clinicians must discuss
Counselling patients on potential ejaculatory and sexual side effects before initiating BPH treatment, particularly 5α-reductase inhibitors, is critical for informed consent and adherence.
Aquablation vs. TURP: Ejaculatory Function Durability in BPH
Robotic waterjet ablation (Aquablation) preserves antegrade ejaculation in BPH patients at significantly higher rates than TURP, with durability up to five years.
Nerve Stimulation's Lasting Impact on Pediatric Bladder Control
Children treated with sacral neuromodulation for bladder dysfunction may experience sustained relief years after therapy cessation. This suggests a potential for long-term benefit beyond active treatment.
Off-label testosterone use: a cardiovascular gamble for men?
Off-label testosterone therapy for men without clear hypogonadism may increase cardiovascular event risk, prompting a re-evaluation of prescribing practices.
Prostatectomy Leakage: The Long Road to Recovery
Urinary leakage after prostate surgery often improves significantly over 12 months, a critical period for patient recovery and quality of life.
Bladder-sphincter dyssynergia: A brainstem switch just flipped our understanding
Estrogen receptor 1-expressing neurons in the pontine micturition center precisely coordinate bladder contraction and urethral sphincter relaxation for urination.