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Patients on lorlatinib should be monitored for hyperglycemia, regardless of autoantibody status. This case raises concerns about potential metabolic toxicities of ALK inhibitors beyond what is currently recognized.

The VICTORION-PLAQUE trial in primary prevention evaluates inclisiran, a small interfering RNA targeting PCSK9, for effects on atherosclerotic plaque using prespecified multimodality imaging endpoints. Randomized and double-blind, with dosing at day 1, day ...