Lymphomas are the most common haematological malignancies, encompassing Hodgkin lymphoma and a diverse spectrum of non-Hodgkin lymphomas. Chemoimmunotherapy remains standard for many subtypes, while CAR-T cell therapy, bispecific antibodies, and novel targeted agents are reshaping options for relapsed/refractory disease. Cell-free DNA and liquid biopsy tools are advancing MRD monitoring and earlier relapse detection.
New Regimen Confers 'Meaningful' Benefit in Aggressive Lymphoma
A novel treatment regimen has demonstrated significant clinical benefit in patients with aggressive lymphoma, potentially establishing a new standard of care.
CAR T: Speed and Reliability Critical for Patient Outcomes
CAR T-cell therapy for glioblastoma multiforme (GBM) requires rapid, reliable delivery to improve patient outcomes, addressing current translational limitations.
DLBCL Management: Bispecific Antibodies as Emerging Therapeutic Option
Current bispecific antibody options in relapsed/refractory DLBCL — including epcoritamab and glofitamab as T-cell engager therapies — reviewed for efficacy, safety, and sequencing after CAR-T or prior lines of therapy.
CAR T-Cell Therapy Guidelines Evolve for Lymphoma, Myeloma at EHA 2026
EHA 2026 discussions highlight evolving CAR T-cell therapy guidelines for lymphoma and multiple myeloma, focusing on patient selection and sequencing.
CD20-Targeted Therapies Remain Central to NHL Management
CD20-directed agents continue to underpin non-Hodgkin lymphoma treatment, with ongoing refinements in antibody-drug conjugates and bispecifics.
Infection Prevention Critical in Hematological Malignancies
Patients with hematological malignancies face a high risk of infection, necessitating proactive prevention strategies to improve outcomes.
Allogeneic Cell Therapy for EBV+ PTLD: EHA 2026 Insights
Allogeneic cell therapy offers a targeted approach for Epstein-Barr virus-positive post-transplant lymphoproliferative disease (EBV+ PTLD). This EHA 2026 review examines its role in clinical management.
Bispecific Antibodies Positioned in Relapsed Follicular Lymphoma
Bispecific antibodies offer new options for relapsed/refractory follicular lymphoma, particularly after two prior lines of therapy.
CAR T Therapy Shows Sustained Efficacy in Relapsed/Refractory Lymphoma
CAR T-cell therapy demonstrates durable responses in relapsed/refractory large B-cell lymphoma, addressing a critical unmet need.