cardiomyopathies

Cardiomyopathies are a diverse group of myocardial diseases, including hypertrophic, dilated, arrhythmogenic, and restrictive subtypes, that frequently lead to heart failure or sudden cardiac death. Genetic testing and cascade family screening are standard practice for most inherited forms. Novel disease-specific treatments, including mavacamten for hypertrophic obstructive cardiomyopathy, are changing the therapeutic landscape.